Activation of M1 macrophages promotes diabetic kidney disease by modulating glycolysis via HIF-1α-HK2 signaling pathway
We demonstrated that M1 macrophage polarization mediated glycolysis contributed to DKD via regulating HIF-1α-HK2 signaling pathway.
Authors
- Zhendong Huang (ORCID: https://orcid.org/0000-0001-8529-0411)
- Langen Zhuang (ORCID: https://orcid.org/0000-0003-3700-2715)
- Xiaoyan Pei (ORCID: https://orcid.org/0000-0001-5404-8614)
- Li Yu (ORCID: https://orcid.org/0000-0002-2221-8911)
- Qiong Wang (ORCID: https://orcid.org/0000-0003-0334-7395)
- Wei Yu (ORCID: https://orcid.org/0009-0003-1501-7980)
- Lijuan Lu (ORCID: https://orcid.org/0000-0002-8465-1024)
- Guoxi Jin (ORCID: https://orcid.org/0000-0001-5944-9142)
- Yanli Yang (ORCID: https://orcid.org/0000-0002-3625-8770)
Institutions
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1186/s13098-025-01894-3
- Citations
- 6
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.78
Funders
- Bengbu Medical College
- Anhui Provincial Key Research and Development Plan