Vancomycin‐Induced Acute Kidney Injury in Intensive Care Patients: A Target Trial Emulation Study Using Multicenter Routinely Collected Data
Our findings indicate that vancomycin causes a higher risk of AKI compared to the alternative antibiotics. We recommend clinicians to be compliant with vancomycin-induced AKI prevention strategies, such as therapeutic drug monitoring or the consideration of an alternative antibiotic if possible.
Authors
- Joanna E. Klopotowska (ORCID: https://orcid.org/0000-0002-9707-5740)
- Dylan W. de Lange (ORCID: https://orcid.org/0000-0002-0191-7270)
- Nicholas C Chesnaye (ORCID: https://orcid.org/0000-0003-4883-9174)
- Izak Yasrebi‐de Kom (ORCID: https://orcid.org/0000-0002-8655-2521)
- Nicolette F. de Keizer (ORCID: https://orcid.org/0000-0002-6651-1730)
- Giovanni Cinà (ORCID: https://orcid.org/0000-0002-3521-8208)
- Kitty J. Jager (ORCID: https://orcid.org/0000-0003-0444-8569)
- Vianda S Stel (ORCID: https://orcid.org/0000-0002-0007-1947)
- Ameen Abu‐Hanna (ORCID: https://orcid.org/0000-0003-4324-7954)
- Dave Anton Dongelmans (ORCID: https://orcid.org/0000-0001-8477-6671)
Institutions
- Amsterdam UMC Location University of Amsterdam (NL)
- University Medical Center Utrecht (NL)
- GGD Amsterdam (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Pharmacoepidemiology and Drug Safety
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1002/pds.70205
- Citations
- 1
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- ZonMw
- Radboud Universiteit
- Radboud Universitair Medisch Centrum