Disseminated intravascular coagulation in pregnancy: a case report

Disseminated intravascular coagulation (DIC) is a life-threatening situation arising from a variety of obstetrical and non-obstetrical causes. Obstetrical causes include postpartum hemorrhage, placental abruption, preeclampsia, HELLP (hemolysis, elevated liver enzymes and low platelets) syndrome, retained stillbirth, septic abortion and intrauterine infection, amniotic fluid embolism and acute fatty liver of pregnancy. Prompt diagnosis and understanding of the underlying mechanism is essential for a favorable outcome. We report a successful pregnancy outcome in a multiparous woman with severe atonic postpartum hemorrhage following normal vaginal delivery managed by obstetric hysterectomy complicated with disseminated intravascular coagulation. Massive blood and blood products transfusion given. Serial monitoring of coagulation profile done- improved on postoperative day 3. Identification of risks and early diagnosis of DIC can prevent maternal morbidity and mortality. Team work and prompt treatment are essential for successful management.

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Publication Details

Journal
International Journal of Reproduction Contraception Obstetrics and Gynecology
Published
2025-08-28
DOI
https://doi.org/10.18203/2320-1770.ijrcog20252761
Primary Topic
Maternal and fetal healthcare
Type
article
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article

Disseminated intravascular coagulation in pregnancy: a case report

Rachel Mathew, Aneetta M. Lalu
International Journal of Reproduction Contraception Obstetrics and Gynecology
Maternal and fetal healthcare
article

Disseminated intravascular coagulation in pregnancy: a case report

Rachel Mathew, Aneetta M. Lalu
article en

Abstract

Disseminated intravascular coagulation (DIC) is a life-threatening situation arising from a variety of obstetrical and non-obstetrical causes. Obstetrical causes include postpartum hemorrhage, placental abruption, preeclampsia, HELLP (hemolysis, elevated liver enzymes and low platelets) syndrome, retained stillbirth, septic abortion and intrauterine infection, amniotic fluid embolism and acute fatty liver of pregnancy. Prompt diagnosis and understanding of the underlying mechanism is essential for a favorable outcome. We report a successful pregnancy outcome in a multiparous woman with severe atonic postpartum hemorrhage following normal vaginal delivery managed by obstetric hysterectomy complicated with disseminated intravascular coagulation. Massive blood and blood products transfusion given. Serial monitoring of coagulation profile done- improved on postoperative day 3. Identification of risks and early diagnosis of DIC can prevent maternal morbidity and mortality. Team work and prompt treatment are essential for successful management.

International Journal of Reproduction Contraception Obstetrics and GynecologyVol. 14(9)
Pushpagiri Medical College (IN)
Openalex Percentile: Top 68%
Maternal and fetal healthcare
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Disseminated intravascular coagulation in pregnancy: a case report — Rachel Mathew, Aneetta M. Lalu · International Journal of Reproduction Contraception Obstetrics and Gynecology (2025) | TGRS Research Map | TGRS