Antimicrobial peptide PK34 modification enhances the antibacterial and anti-inflammatory effects of bone-derived mesenchymal stem cells in Mycobacterium tuberculosis infection
PK34 modification enhanced the therapeutic efficacy of MSCs in Mtb infection models, and Plent-PK34-BMSCs transplantation has the potential to treat TB.
Authors
- Y.-J. Sun (ORCID: https://orcid.org/0000-0003-0454-1229)
- Chun‐Ping Cui (ORCID: https://orcid.org/0000-0003-0251-3259)
- Tingxun Yuan
- Zhongyan Wang (ORCID: https://orcid.org/0000-0003-2967-719X)
- Qian Li (ORCID: https://orcid.org/0000-0002-7296-6248)
- Wei Gao (ORCID: https://orcid.org/0000-0003-1026-3878)
- Yiming Liu
- Xiang Zhao (ORCID: https://orcid.org/0000-0002-9353-6896)
- Chen Yao (ORCID: https://orcid.org/0000-0003-4224-5535)
- He Xinyu
- Zhengjun Yi (ORCID: https://orcid.org/0000-0003-3922-3386)
- Jiaqi Wang (ORCID: https://orcid.org/0009-0008-7293-3156)
- Yang Cai
Institutions
- Weifang Medical University (CN)
- Heze Municipal Hospital (CN)
- Shandong Academy of Sciences (CN)
- Beijing Proteome Research Center (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1186/s13287-025-04596-9
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- Program for Innovation Team Building at Institutions of Higher Education in Chongqing