Association of obesity and adrenal androgen levels with bone age progression in boys with premature adrenarche
In boys with PA, higher DHEA-S z-scores and BMI z-scores were associated with BA-CA. However, DHEA-S did not mediate the relationship between obesity and BA progression. Our data suggested that in boys with obesity and PA, the rapid progression of skeletal maturation is primarily the result of a direct impact of obesity on BA and not due to an increase in adrenal androgen levels.
Authors
- Seung Yang (ORCID: https://orcid.org/0000-0002-3380-6962)
- Kyeongmi Lee (ORCID: https://orcid.org/0000-0001-7525-0897)
- Yunsoo Choe (ORCID: https://orcid.org/0000-0001-9396-1676)
- Jinjoo Choi (ORCID: https://orcid.org/0000-0003-2179-5802)
Institutions
- Hanyang University Guri Hospital (KR)
- Hanyang University Seoul Hospital (KR)
- Hanyang University (KR)
Publication Details
- Journal
- Annals of Pediatric Endocrinology & Metabolism
- Published
- 2025-08-28
- DOI
- https://doi.org/10.6065/apem.2448248.124
- Citations
- 1
- Primary Topic
- Hypothalamic control of reproductive hormones
- Type
- article
- Field-Weighted Citation Impact
- 1.70