Laboratory Identification of Lupus Anticoagulant ( <scp>LA</scp> ) Using Different Activated Partial Thromboplastin Time ( <scp>APTT</scp> ) Assays
We observed a good agreement between PTT-LA/Staclot LA and Dade Actin FSL/FS, and fair to moderate agreement with HemosIL SCT, whose performance improved with increasing phospholipid concentration. These results demonstrate that all three assays are comparable for APTT-LA detection.
Authors
- Vanderson Rocha (ORCID: https://orcid.org/0000-0003-0094-619X)
- Maria Paula
- Paula Ribeiro Villaça (ORCID: https://orcid.org/0000-0003-0689-4511)
- Fernanda Andrade Orsi (ORCID: https://orcid.org/0000-0002-7908-9073)
- Bianca Stefanello (ORCID: https://orcid.org/0000-0002-0650-6833)
- Bárbara Gomes Barion (ORCID: https://orcid.org/0000-0002-1669-3820)
- Tânia Rúbia Flores da Rocha (ORCID: https://orcid.org/0000-0001-5596-1640)
- Thaís Siemerink Saraiva
Institutions
- Universidade de São Paulo (BR)
- Universidade Estadual de Campinas (UNICAMP) (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- International Journal of Laboratory Hematology
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1111/ijlh.14549
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Universidade de São Paulo
- Faculdade de Medicina da Universidade de São Paulo
- Siemens Healthineers