Bipolar spectrum, hypothyroidism, and their association with chronic fatigue/myalgic encephalomyelitis-like syndrome in long COVID: could they be identified as early determinants?

The findings suggest that hypothyroidism and bipolar spectrum disorders may act as predisposing factors in the development of CFS/ME in long-term COVID-19. Identifying these clinical antecedents could facilitate early detection and the development of targeted intervention strategies in at-risk populations.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2025-08-28
DOI
https://doi.org/10.3389/fpsyt.2025.1623288
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
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article

Bipolar spectrum, hypothyroidism, and their association with chronic fatigue/myalgic encephalomyelitis-like syndrome in long COVID: could they be identified as early determinants?

Felice Curcio, Cesar Iván Avilés González, Şükrü Dursun, Giulia Cossu et al.
1 links
Frontiers in Psychiatry
Long-Term Effects of COVID-19
article

Bipolar spectrum, hypothyroidism, and their association with chronic fatigue/myalgic encephalomyelitis-like syndrome in long COVID: could they be identified as early determinants?

Felice Curcio, Cesar Iván Avilés González, Şükrü Dursun, Giulia Cossu, Massimo Tusconi, Mauro Giovanni Carta, Lina Patricia Camacho Nunez, Adriana Pilar Zambrano Ochoa, Vanessa Barrui, Lluís Luján, Francesco Pegreffi, Michele Fornaro
article en

Abstract

The findings suggest that hypothyroidism and bipolar spectrum disorders may act as predisposing factors in the development of CFS/ME in long-term COVID-19. Identifying these clinical antecedents could facilitate early detection and the development of targeted intervention strategies in at-risk populations.

Frontiers in PsychiatryVol. 16
University of Alberta (CA), University of Sassari (IT), University of Cagliari (IT), Università degli Studi di Enna Kore (IT), Popular University of Cesar (CO), Federico II University Hospital (IT), Azienda Sanitaria Locale Roma 3 (IT), University of Naples Federico II (IT)
Fondazione di Sardegna
Openalex Percentile: Top 67%
Long-Term Effects of COVID-19
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Bipolar spectrum, hypothyroidism, and their association with chronic fatigue/myalgic encephalomyelitis-like syndrome in long COVID: could they be identified as early determinants? — Felice Curcio, Cesar Iván Avilés González, et al. · Frontiers in Psychiatry (2025) | TGRS Research Map | TGRS