Implementation of a stepwise process for somatic testing in patients with a new diagnosis of germline negative epithelial ovarian cancer

We successfully increased somatic testing recommendations in germline BRCA negative patients prior to completing upfront EOC treatment allowing for a timely, individualized discussion of maintenance PARP inhibitor use. Qualitative assessment of patients' comprehension of genetic testing for EOC shows a deficit in patient knowledge.

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Publication Details

Journal
Gynecologic Oncology Reports
Published
2025-08-28
DOI
https://doi.org/10.1016/j.gore.2025.101935
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

Implementation of a stepwise process for somatic testing in patients with a new diagnosis of germline negative epithelial ovarian cancer

Laura Ongie, Vonda Wall, Sanjna Rajput, Myra Wick et al.
Gynecologic Oncology Reports
PARP inhibition in cancer therapy
article

Implementation of a stepwise process for somatic testing in patients with a new diagnosis of germline negative epithelial ovarian cancer

Laura Ongie, Vonda Wall, Sanjna Rajput, Myra Wick, Clarissa Polen-De, Karen Schaepe, Amanika Kumar, Sara Klennert, Megan E. Grudem, Kristin Cole, Carolyn M. Klampe, Casey Lawler
article en

Abstract

We successfully increased somatic testing recommendations in germline BRCA negative patients prior to completing upfront EOC treatment allowing for a timely, individualized discussion of maintenance PARP inhibitor use. Qualitative assessment of patients' comprehension of genetic testing for EOC shows a deficit in patient knowledge.

Gynecologic Oncology ReportsVol. 61
Mayo Clinic (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Zero hunger
Openalex Percentile: Top 68%
PARP inhibition in cancer therapy
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Implementation of a stepwise process for somatic testing in patients with a new diagnosis of germline negative epithelial ovarian cancer — Laura Ongie, Vonda Wall, et al. · Gynecologic Oncology Reports (2025) | TGRS Research Map | TGRS