“Two-stage resection of synchronous liver metastases in colorectal cancer leads to a survival benefit: a retrospective comparative cohort study”
Primary tumor resection before liver resection appears to improve long-term survival in CRLM patients. Simultaneous resection should be carefully considered due to increased mortality, particularly in older patients with lower performance status undergoing major liver surgery. Postoperative chemotherapy enhances survival, emphasizing the need for tailored treatment strategies.
Authors
- Stephan Gretschel (ORCID: https://orcid.org/0000-0001-8151-4932)
- Andreas Loew
- Sebastian Lünse (ORCID: https://orcid.org/0000-0002-7611-1802)
- Anne von Ruesten
- René Mantke (ORCID: https://orcid.org/0000-0001-5590-6019)
- Constanze Schneider
Institutions
- Medizinische Hochschule Brandenburg Theodor Fontane (DE)
- Universitätsklinikum Brandenburg an der Havel (DE)
- Brandenburg University of Technology Cottbus-Senftenberg (DE)
Publication Details
- Journal
- Langenbeck s Archives of Surgery
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1007/s00423-025-03840-3
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00