Jiangtang Decoction for Type 2 Diabetes and NAFLD: Integrative Analysis via Network Pharmacology, Mendelian Randomization, Molecular Docking, and In Vitro Validation

This study identified eight genes that are genetically predicted to be causal for the therapeutic effects of JTD on both T2DM and NAFLD, thereby establishing a genetic link between the conditions. These targets and associated pathways illuminate common underlying mechanisms, supporting JTD's potential for integrated treatment strategies and providing a basis for further investigation.

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Publication Details

Journal
Endocrine Metabolic & Immune Disorders - Drug Targets
Published
2025-08-22
DOI
https://doi.org/10.2174/0118715303424915250818045151
Citations
1
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
1.50
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article

Jiangtang Decoction for Type 2 Diabetes and NAFLD: Integrative Analysis via Network Pharmacology, Mendelian Randomization, Molecular Docking, and In Vitro Validation

Siying Weng, Wenbo Gong, Xiaoyan Lu
1 citations
Endocrine Metabolic & Immune Disorders - Drug Targets
Computational Drug Discovery Methods
1.50
article

Jiangtang Decoction for Type 2 Diabetes and NAFLD: Integrative Analysis via Network Pharmacology, Mendelian Randomization, Molecular Docking, and In Vitro Validation

Siying Weng, Wenbo Gong, Xiaoyan Lu
article en
1 citations

Abstract

This study identified eight genes that are genetically predicted to be causal for the therapeutic effects of JTD on both T2DM and NAFLD, thereby establishing a genetic link between the conditions. These targets and associated pathways illuminate common underlying mechanisms, supporting JTD's potential for integrated treatment strategies and providing a basis for further investigation.

Endocrine Metabolic & Immune Disorders - Drug TargetsVol. 25
Zhejiang Chinese Medical University (CN)
Openalex Percentile: Top 14%
Computational Drug Discovery Methods
1.50
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