Quality Assurance of Omega-3 Fatty Acids in Fish Oil Capsules

Omega-3 long-chain Polyunsaturated Fatty Acids (n-3 PUFAs) found in fish oil capsules have a critical role and significance for human health.Particularly EPA and DHA are known for their potential benefits in preventing cardiovascular disease, treating inflammatory conditions, improving early life neurodevelopment, and preventing cognitive decline.n-3 PUFAs are highly prone to oxidation and degradation reactions due to their chemical structure containing several double bonds.Here, we emphasize the importance of quality assurance in the production of omega-3 capsules, from raw material extraction to manufacturing, packaging, and storage.Oxidation protection is identified as a key factor in preserving the freshness and efficacy of omega-3 products.Various factors influencing oxidation are discussed, including exposure to air, temperature, time, light, transition metals, and water.The role of antioxidants in reducing oxidation is highlighted and the importance of monitoring oxidation levels through tests like the TOTOX value.The article emphasizes the need for proper storage, handling and testing of omega-3 capsules to ensure their quality and effectiveness for consumers.The review provides a comprehensive analysis of the literature on omega-3 fatty acids and underscores the significance of quality assurance in delivering high-quality omega-3 products.