<scp>NSUN2</scp> ‐mediated <scp> m <sup>5</sup> C </scp> methylation modification regulates trophoblast cell proliferation, apoptosis, and autophagy in gestational diabetes mellitus
NSUN2-mediated m<sup>5</sup>C modification promoted GDM progression by upregulating PINK1 expression, leading to impaired trophoblast function. Targeting this NSUN2-m<sup>5</sup>C-PINK1 axis may represent a promising therapeutic strategy for GDM management.
Authors
- Zhaozhao Li
- Jiujiu Liu
- Dapeng Wang (ORCID: https://orcid.org/0000-0002-5746-4987)
- Yingjun Chen (ORCID: https://orcid.org/0000-0002-4784-8282)
Institutions
- Beijing Fengtai Hospital (CN)
Publication Details
- Journal
- Journal of Diabetes Investigation
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1111/jdi.70140
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81