Non-Hodgkin's Lymphoma in Pregnancy: A Report of a Rare Case

Non-Hodgkin's lymphoma is a rare diagnosis observed in pregnant women. It can present as B-cell and T-cell lymphomas. It can be a diagnostic challenge in pregnant women, due to overlapping clinical features such as weight loss and fatigue, similar to pregnancy. It can be managed either by immediate intervention in aggressive cases or after postpartum if indolent. We present the case of a 30-year-old woman at 32 weeks of gestation, presenting with a painless progressive swelling over the left side of her neck. It was later diagnosed as non-Hodgkin's lymphoma and successfully managed by R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone).

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Journal
Cureus
Published
2025-08-28
DOI
https://doi.org/10.7759/cureus.91156
Primary Topic
Cancer Risks and Factors
Type
article
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article

Non-Hodgkin's Lymphoma in Pregnancy: A Report of a Rare Case

Apoorva B Patil, SyedNawaz Ahmad, Barathi Raja Kuppusami
Cureus
Cancer Risks and Factors
article

Non-Hodgkin's Lymphoma in Pregnancy: A Report of a Rare Case

Apoorva B Patil, SyedNawaz Ahmad, Barathi Raja Kuppusami
article en

Abstract

Non-Hodgkin's lymphoma is a rare diagnosis observed in pregnant women. It can present as B-cell and T-cell lymphomas. It can be a diagnostic challenge in pregnant women, due to overlapping clinical features such as weight loss and fatigue, similar to pregnancy. It can be managed either by immediate intervention in aggressive cases or after postpartum if indolent. We present the case of a 30-year-old woman at 32 weeks of gestation, presenting with a painless progressive swelling over the left side of her neck. It was later diagnosed as non-Hodgkin's lymphoma and successfully managed by R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone).

CureusVol. 17(8)
Sree Balaji Dental College and Hospital (IN)
Good health and well-being
Openalex Percentile: Top 68%
Cancer Risks and Factors
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