Consider the unexpected! An overlooked, elusive, rare but dramatic diagnosis: anorectal melanoma
AM is frequently overlooked due to its rarity and non-specific presentation. Earlier recognition alone may not improve outcomes, but systematic histopathological assessment, targeted biopsy, and multidisciplinary management remain essential. Conservative surgery with early use of systemic therapy should be prioritized when feasible.
Authors
- Daniela Rega (ORCID: https://orcid.org/0000-0001-8326-050X)
- Carmen Cantisani (ORCID: https://orcid.org/0000-0003-2181-951X)
- Giovanni Paolino (ORCID: https://orcid.org/0000-0002-3032-2217)
- Luciano Giacomelli (ORCID: https://orcid.org/0000-0003-3598-7522)
- Domenico Mascagni (ORCID: https://orcid.org/0000-0002-6606-4539)
- Corrado Caracò (ORCID: https://orcid.org/0000-0002-7828-079X)
- Leonardo Vincenti (ORCID: https://orcid.org/0000-0002-8330-7889)
- Chiara Scorziello (ORCID: https://orcid.org/0000-0003-1823-2961)
- Rebecca Senetta (ORCID: https://orcid.org/0000-0001-8419-4591)
- Chiara Eberspacher (ORCID: https://orcid.org/0000-0001-7973-6990)
- Massimiliano Mistrangelo (ORCID: https://orcid.org/0000-0001-8506-6794)
- Santo Raffaele Mercuri (ORCID: https://orcid.org/0000-0002-9175-4574)
- Marco Biffoni (ORCID: https://orcid.org/0000-0002-7905-0881)
- Pietro Quaglino (ORCID: https://orcid.org/0000-0003-4185-9586)
- Rossella Melcarne (ORCID: https://orcid.org/0000-0002-2820-7607)
- Arcangelo Picciariello (ORCID: https://orcid.org/0000-0002-6361-1111)
- Stefano Arcieri (ORCID: https://orcid.org/0000-0001-6530-0440)
- Paolo Delrio
- Tal Deborah Engel
- Mariarosaria Portinaio
Institutions
- University of Salento (IT)
- Vita-Salute San Raffaele University (IT)
- Policlinico Umberto I (IT)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Department of Medical Sciences (RU)
- Federico II University Hospital (IT)
- IRCCS Ospedale San Raffaele (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Gastroenterology Hospital "Saverio de Bellis" (IT)
- University of Turin (IT)
- University of Naples Federico II (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Updates in Surgery
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1007/s13304-025-02367-y
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00