The Biological Variation in Serum ACE and CPN/CPB2 Activity in Healthy Individuals as Measured by the Degradation of Dabsylated Bradykinin—Reference Data and the Importance of Pre-Analytical Standardization
The results reiterate the critical importance of a high level of standardization in pre-analytical sample collection and processing-most notably, sample quality should be evaluated before conducting any large and expensive omics analyses.
Authors
- Malte Bayer (ORCID: https://orcid.org/0000-0003-1060-8856)
- Michael Snyder (ORCID: https://orcid.org/0000-0003-0784-7987)
- Simone Koenig (ORCID: https://orcid.org/0000-0003-0672-7246)
Institutions
- University of Münster (DE)
- University Hospitals of the Ruhr-University of Bochum (DE)
- Universitätsklinikum Knappschaftskrankenhaus Bochum (DE)
- Stanford University (US)
Publication Details
- Journal
- Proteomes
- Published
- 2025-08-27
- DOI
- https://doi.org/10.3390/proteomes13030040
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Westfälische Wilhelms-Universität Münster
- Brock University