Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics
The LA risk model constructed in this study can effectively predict the prognosis of prostate cancer and is expected to become a new type of test scoring criterion. KCNMA1 is expected to become a novel target for prostate cancer.
Authors
- Mingdong Wang (ORCID: https://orcid.org/0000-0003-1797-9705)
- Ziteng Zhang
- Fengle Zhu (ORCID: https://orcid.org/0000-0002-5449-5788)
- Yongchen Jin
- Fan Zou (ORCID: https://orcid.org/0000-0002-4471-2865)
- Jinming Qiu
- Yishan Zhang (ORCID: https://orcid.org/0009-0008-8856-0999)
- Hao Ping (ORCID: https://orcid.org/0000-0003-2912-0965)
- Fu Yi (ORCID: https://orcid.org/0000-0002-5500-838X)
- Hua Ye
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Chinese Institute for Brain Research (CN)
- Ministry of Science and Technology (VN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1186/s12967-025-06990-6
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China