<i>Mycobacterium Intracellulare</i> Infection of the Metacarpophalangeal Joint in a Patient With Rheumatoid Arthritis: A Case Report

<b>Background:</b> Nontuberculous <i>Mycobacterium</i> (NTM) infections affecting musculoskeletal structures are rare, particularly in patients with well-controlled rheumatoid arthritis (RA). This case is reported to highlight the potential risk of focal tenosynovitis due to <i>Mycobacterium intracellulare</i> following intra-articular glucocorticoid injection. <b>Case presentation:</b> A 79-year-old man with well-controlled RA developed tenosynovitis with bone destruction in the right index finger metacarpophalangeal joint following a single intra-articular injection of triamcinolone acetonide. Despite antibiotic treatment, the condition progressively worsened. Synovectomy revealed <i>Mycobacterium intracellulare</i> infection involving both flexor tendons, joint space, and bone marrow. The patient regularly engaged in gardening activities without protective gloves. <b>Conclusion:</b> This case highlights the importance of considering NTM infection in the differential diagnosis of persistent monoarthritis that worsens after intra-articular glucocorticoid injection, especially in patients with exposure risk factors such as gardening.

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Journal
Case Reports in Rheumatology
Published
2025-01-01
DOI
https://doi.org/10.1155/crrh/1818066
Citations
1
Primary Topic
Mycobacterium research and diagnosis
Type
article
Field-Weighted Citation Impact
1.35
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article

Mycobacterium Intracellulare Infection of the Metacarpophalangeal Joint in a Patient With Rheumatoid Arthritis: A Case Report

Ryosuke Hanaoka
1 citations
Case Reports in Rheumatology
Mycobacterium research and diagnosis
1.35
article

Mycobacterium Intracellulare Infection of the Metacarpophalangeal Joint in a Patient With Rheumatoid Arthritis: A Case Report

Ryosuke Hanaoka
article en
1 citations

Abstract

<b>Background:</b> Nontuberculous <i>Mycobacterium</i> (NTM) infections affecting musculoskeletal structures are rare, particularly in patients with well-controlled rheumatoid arthritis (RA). This case is reported to highlight the potential risk of focal tenosynovitis due to <i>Mycobacterium intracellulare</i> following intra-articular glucocorticoid injection. <b>Case presentation:</b> A 79-year-old man with well-controlled RA developed tenosynovitis with bone destruction in the right index finger metacarpophalangeal joint following a single intra-articular injection of triamcinolone acetonide. Despite antibiotic treatment, the condition progressively worsened. Synovectomy revealed <i>Mycobacterium intracellulare</i> infection involving both flexor tendons, joint space, and bone marrow. The patient regularly engaged in gardening activities without protective gloves. <b>Conclusion:</b> This case highlights the importance of considering NTM infection in the differential diagnosis of persistent monoarthritis that worsens after intra-articular glucocorticoid injection, especially in patients with exposure risk factors such as gardening.

Case Reports in RheumatologyVol. 2025(1)
Kamituga General Hospital (JP)
Openalex Percentile: Top 16%
Mycobacterium research and diagnosis
1.35
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<i>Mycobacterium Intracellulare</i> Infection of the Metacarpophalangeal Joint in a Patient With Rheumatoid Arthritis: A Case Report — Ryosuke Hanaoka · Case Reports in Rheumatology (2025) | TGRS Research Map | TGRS