Associations between 1400 metabolites and subtypes of endometriosis: a two-sample Mendelian randomisation study
Our study suggests potential causal relationships between metabolites and various endometriosis subtypes from an MR perspective. However, the limited number of associations that survived multiple-testing correction indicates that these findings are preliminary and require validation in larger cohorts. This exploratory analysis may contribute to advancing future research on metabolomics-based diagnosis, treatment, and prevention of endometriosis.
Authors
- Zhijie Huang (ORCID: https://orcid.org/0000-0002-7312-4982)
- Lingfeng Wu
- Zhouxiang Chen (ORCID: https://orcid.org/0009-0006-9509-2674)
- Fei Yan (ORCID: https://orcid.org/0000-0002-3304-4718)
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Riverside Hospital of Guangxi Zhuang Autonomous Region (CN)
- Hezhou University (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Journal of Obstetrics and Gynaecology
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1080/01443615.2025.2552402
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00