Optical coherence tomography – A possible biomarker in early huntington’s disease

HD patients exhibit significantly thinner retinal ganglion cell inner plexiform layer and macular retinal nerve fibre layer compared to HC, even in the early phase of the disease. These findings suggest that OCT may serve as a valuable biomarker to monitor neurodegeneration at an early disease stage.

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Publication Details

Journal
Neurological Research and Practice
Published
2025-08-28
DOI
https://doi.org/10.1186/s42466-025-00421-z
Citations
1
Primary Topic
Genetic Neurodegenerative Diseases
Type
article
Field-Weighted Citation Impact
0.91
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OCT
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Optical coherence tomography – A possible biomarker in early huntington’s disease

Atbin Djamshidian, Katarína Schwarzová, Gabriel Bsteh, Beatrice Heim et al.
1 citations
Neurological Research and Practice
Genetic Neurodegenerative Diseases
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article

Optical coherence tomography – A possible biomarker in early huntington’s disease

Atbin Djamshidian, Katarína Schwarzová, Gabriel Bsteh, Beatrice Heim, Marina Peball, E. Mandler, Barbara Teuchner, Klaus Seppi, Federico Carbone, Clancy Cerejo
article en
1 citations

Abstract

HD patients exhibit significantly thinner retinal ganglion cell inner plexiform layer and macular retinal nerve fibre layer compared to HC, even in the early phase of the disease. These findings suggest that OCT may serve as a valuable biomarker to monitor neurodegeneration at an early disease stage.

Neurological Research and PracticeVol. 7(1)
Innsbruck Medical University (AT), Universität Innsbruck (AT), Medical University of Vienna (AT), University of Applied Sciences Kufstein (AT)
Openalex Percentile: Top 23%
Genetic Neurodegenerative Diseases
0.91
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