Data‐Driven Cluster Analysis of Cerebrospinal Fluid Proteome and Associations with Clinical Phenotypes in Systemic Lupus Erythematosus
Patients clustered by their CSF proteomic pattern had different disease phenotypes. Nephritis and neuronal damage defined the group with higher levels of neuronal proteins in CSF, which may suggest shared pathogenetic pathways in SLE affecting the kidney and CNS.
Authors
- Robin Kahn (ORCID: https://orcid.org/0000-0002-3167-1179)
- Birgitta Gullstrand (ORCID: https://orcid.org/0000-0002-9172-990X)
- Andreas Jönsen (ORCID: https://orcid.org/0000-0002-4418-5786)
- Seyed Morteza Najibi (ORCID: https://orcid.org/0000-0001-6756-508X)
- Kristoffer A. Zervides (ORCID: https://orcid.org/0000-0003-4311-1635)
- Charlotte Welinder (ORCID: https://orcid.org/0000-0001-9626-0576)
- Jessika Nystedt (ORCID: https://orcid.org/0000-0002-7193-1828)
- Pia C. Sundgren (ORCID: https://orcid.org/0000-0001-9237-1236)
- Elsa Grenmyr (ORCID: https://orcid.org/0009-0001-2638-401X)
- Anders Bengtsson (ORCID: https://orcid.org/0000-0001-7752-0432)
- Petra C Nilsson
Institutions
- Lund University (SE)
- SpectraCure (Sweden) (SE)
- Skåne University Hospital (SE)
Publication Details
- Journal
- ACR Open Rheumatology
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1002/acr2.70089
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alfred Österlunds Stiftelse
- Magnus Bergvalls Stiftelse
- Reumatikerförbundet