An Advanced‐Stage Encapsulated Papillary Breast Carcinoma in a Male: A Case Report

Encapsulated papillary carcinoma (EPC) is an invasive carcinoma which shows papillary architecture within a thickened fibrous capsule. Multiple studies have shown that this tumor follows an indolent course with excellent prognosis, and as such, it is recommended that it be staged as in situ lesions. It is an uncommonly encountered tumor most often diagnosed in postmenopausal females. As breast cancer in males is overall rare, available data on diagnosis, management, and outcomes of EPC in males is limited. Typically, cases of EPC that present with advanced stage and/or lymph node metastases show an associated invasive process. We present a case of pure EPC in a male patient with associated skin ulceration and positive lymph nodes, leading to a final stage of ypT4bN1a. The present report underscores the indolent nature of EPC, even when diagnosed at an advanced stage.

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Publication Details

Journal
Case Reports in Pathology
Published
2025-01-01
DOI
https://doi.org/10.1155/crip/6518104
Primary Topic
Male Breast Health Studies
Type
article
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article

An Advanced‐Stage Encapsulated Papillary Breast Carcinoma in a Male: A Case Report

Stephanie C. Fine, Mary Torrez, Nadja K. Falk, Jain Zhou et al.
Case Reports in Pathology
Male Breast Health Studies
article

An Advanced‐Stage Encapsulated Papillary Breast Carcinoma in a Male: A Case Report

Stephanie C. Fine, Mary Torrez, Nadja K. Falk, Jain Zhou, Elyssa Glassheim
article en

Abstract

Encapsulated papillary carcinoma (EPC) is an invasive carcinoma which shows papillary architecture within a thickened fibrous capsule. Multiple studies have shown that this tumor follows an indolent course with excellent prognosis, and as such, it is recommended that it be staged as in situ lesions. It is an uncommonly encountered tumor most often diagnosed in postmenopausal females. As breast cancer in males is overall rare, available data on diagnosis, management, and outcomes of EPC in males is limited. Typically, cases of EPC that present with advanced stage and/or lymph node metastases show an associated invasive process. We present a case of pure EPC in a male patient with associated skin ulceration and positive lymph nodes, leading to a final stage of ypT4bN1a. The present report underscores the indolent nature of EPC, even when diagnosed at an advanced stage.

Case Reports in PathologyVol. 2025(1)
University of New Mexico (US)
Openalex Percentile: Top 69%
Male Breast Health Studies
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An Advanced‐Stage Encapsulated Papillary Breast Carcinoma in a Male: A Case Report — Stephanie C. Fine, Mary Torrez, et al. · Case Reports in Pathology (2025) | TGRS Research Map | TGRS