Evaluation of p53 Gene Mutations in Oral Lichen Planus Lesions in a Population From Iran
The study identified p53 gene mutations in 21% of oral lichen planus (OLP) cases, with no demographic or pathological correlations. While highlighting p53's complex role and potential as a biomarker, limited sample size necessitates larger, multi-center studies to clarify genetic/environmental influences on OLP pathogenesis and mutation predisposition.
Authors
- Rouhallah Najjar Sadeghi (ORCID: https://orcid.org/0000-0002-1785-7751)
- Maryam Seyedmajidi (ORCID: https://orcid.org/0000-0002-4671-4231)
- Atena Shiva (ORCID: https://orcid.org/0000-0002-0584-1859)
- Erfan Jokar
- Mohamad Kazem Radaei
- Vahid Poladvand
- Abouzar Bagheri Haroni
Institutions
- University of Jiroft (IR)
- Babol University of Medical Sciences (IR)
- Mazandaran University of Medical Sciences (IR)
Publication Details
- Journal
- Clinical and Experimental Dental Research
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1002/cre2.70206
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mazandaran University of Medical Sciences