Presence of interictal epileptiform EEG discharges implies increased risk of recurrence after the first unprovoked seizure: Report of the International League Against Epilepsy and International Federation of Clinical Neurophysiology
In conclusion, the presence of IEDs in EEG recordings obtained after the first unprovoked seizure can help clinicians to confirm the clinical diagnosis of epilepsy after a first unprovoked seizure, according to the revised ILAE definition. These results support the relevance of IED detection on EEG as a predictor of seizure recurrence after a first unprovoked seizure. However, its prognostic value is influenced by age and other clinical factors.
Authors
- Michalis Koutroumanidis (ORCID: https://orcid.org/0000-0002-5616-6240)
- Samuel Wiebe (ORCID: https://orcid.org/0000-0002-1061-9099)
- Sándor Beniczky (ORCID: https://orcid.org/0000-0002-6035-6581)
- Margitta Seeck (ORCID: https://orcid.org/0000-0002-6702-0167)
- Betül Baykan (ORCID: https://orcid.org/0000-0002-3360-659X)
- Louis Maillard (ORCID: https://orcid.org/0000-0003-2895-0385)
- John Dunne (ORCID: https://orcid.org/0000-0002-1283-4374)
Institutions
- Centre National de la Recherche Scientifique (FR)
- St Thomas' Hospital (GB)
- University of Calgary (CA)
- The University of Western Australia (AU)
- Aarhus University (DK)
- Royal Perth Hospital (AU)
- University Hospital of Geneva (CH)
- Istanbul University (TR)
- Université de Lorraine (FR)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1111/epi.18591
- Citations
- 3
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Innovationsfonden
- European Commission
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Danmarks Frie Forskningsfond
- HORIZON EUROPE Framework Programme
- Eurostars