Mapping the FOXA1 Interactome in ER+ Breast Cancer Cells Using Proximity Labeling Reveals Novel Interactions with the Orphan Nuclear Receptor NR2C2
These findings expand the FOXA1 interactome in breast cancer and uncover new candidate proteins with potential as biomarkers and therapeutic targets in hormone-driven tumors.
Authors
- Ingrid M. Montes‐Rodríguez (ORCID: https://orcid.org/0000-0002-3289-9597)
- Rosemary N. Plagens (ORCID: https://orcid.org/0000-0001-5832-9501)
- Christine A. Mills (ORCID: https://orcid.org/0000-0003-0372-4154)
- Hector L. Franco (ORCID: https://orcid.org/0000-0001-9354-0679)
- Julie Dutil (ORCID: https://orcid.org/0000-0002-0313-6443)
- Natalia Maldonado-Vazquez (ORCID: https://orcid.org/0009-0000-3843-9498)
- Carla R. Tirado (ORCID: https://orcid.org/0000-0001-6826-6436)
- Laura E. Herring (ORCID: https://orcid.org/0000-0003-4496-7312)
- Shen Li (ORCID: https://orcid.org/0000-0003-2947-3787)
Institutions
- University of North Carolina at Chapel Hill (US)
- University of North Carolina Health Care (US)
- University of Puerto Rico System (PR)
- Clinical Research Puerto Rico (PR)
Publication Details
- Journal
- Molecular Cancer Research
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1158/1541-7786.mcr-25-0085
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00