Flavonoid Quercetin Enhances Nuclear Factor Erythroid 2-Related Factor 2 Pathway Activation and Reduces Inflammatory Cytokines in Asthmatic Airway Epithelial Cells
This study suggests that quercetin may be a promising therapeutic agent to improve health outcomes in asthma by activating the Nrf2 pathway to reduce oxidative stress and pro-inflammatory cytokines in airway epithelium, which warrants further mechanistic and clinical investigation.
Authors
- Stephanie N. Dawrs
- Christopher A Mancuso (ORCID: https://orcid.org/0000-0003-3081-2758)
- Daniel Winnica (ORCID: https://orcid.org/0000-0002-3612-7949)
- Shuyu Ye
- Fernando Hoguin
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1159/000548106
- Citations
- 3
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.49