Flavonoid Quercetin Enhances Nuclear Factor Erythroid 2-Related Factor 2 Pathway Activation and Reduces Inflammatory Cytokines in Asthmatic Airway Epithelial Cells

This study suggests that quercetin may be a promising therapeutic agent to improve health outcomes in asthma by activating the Nrf2 pathway to reduce oxidative stress and pro-inflammatory cytokines in airway epithelium, which warrants further mechanistic and clinical investigation.

Authors

Publication Details

Journal
International Archives of Allergy and Immunology
Published
2025-08-22
DOI
https://doi.org/10.1159/000548106
Citations
3
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
3.49
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article

Flavonoid Quercetin Enhances Nuclear Factor Erythroid 2-Related Factor 2 Pathway Activation and Reduces Inflammatory Cytokines in Asthmatic Airway Epithelial Cells

Stephanie N. Dawrs, Christopher A Mancuso, Daniel Winnica, Shuyu Ye et al.
3 citations
International Archives of Allergy and Immunology
Asthma and respiratory diseases
3.49
article

Flavonoid Quercetin Enhances Nuclear Factor Erythroid 2-Related Factor 2 Pathway Activation and Reduces Inflammatory Cytokines in Asthmatic Airway Epithelial Cells

Stephanie N. Dawrs, Christopher A Mancuso, Daniel Winnica, Shuyu Ye, Fernando Hoguin
article en
3 citations

Abstract

This study suggests that quercetin may be a promising therapeutic agent to improve health outcomes in asthma by activating the Nrf2 pathway to reduce oxidative stress and pro-inflammatory cytokines in airway epithelium, which warrants further mechanistic and clinical investigation.

International Archives of Allergy and Immunology
Openalex Percentile: Top 7%
Asthma and respiratory diseases
3.49
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