Classic pathway persistent complement activation is associated with specific symptoms in individuals with post–COVID-19 condition: A case-control study
This explorative case-control study did not observe overall complement activation from classic pathway in survivors with post-COVID-19 condition up to 2 years after. Some complement proteins were elevated in individuals with specific post-COVID symptoms, such as fatigue or dyspnea.
Authors
- Beatriz Colom-Fernández
- César Fernández‐de‐las‐Peñas (ORCID: https://orcid.org/0000-0003-3772-9690)
- Carlos Lumbreras (ORCID: https://orcid.org/0000-0003-4748-8288)
- Lars Arendt‐Nielsen (ORCID: https://orcid.org/0000-0003-0892-1579)
- Fernando Cava-Valenciano
- Estíbaliz Arrieta-Ortubay
- Laura Esparcia-Pinedo
- María Ruiz‐Ruigómez (ORCID: https://orcid.org/0000-0003-1538-3043)
- Juan Torres‐Macho (ORCID: https://orcid.org/0000-0002-8860-6837)
- Míriam Akasbi‐Moltalvo
- Dr Med Anabel Franco-Moreno
Institutions
- Universidad Complutense de Madrid (ES)
- Synlab Czech (Czechia) (CZ)
- Universidad Rey Juan Carlos (ES)
- Aalborg University Hospital (DK)
- Hospital Universitario 12 De Octubre (ES)
- Hospital Universitario Infanta Leonor (ES)
- Aalborg University (DK)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1016/j.ijid.2025.108032
- Citations
- 1
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Comunidad de Madrid
- Novo Nordisk
- Novo Nordisk Fonden
- European Regional Development Fund