The effects of empagliflozin on diuresis and natriuresis in patients with type 2 diabetes mellitus and liver cirrhosis

Up to 6 months' empagliflozin administration in patients with cirrhosis and T2DM seems safe and increases urine output and FE<sub>Na</sub>, but its impact on renal function requires further investigation. Larger randomized controlled trials are needed to confirm its long-term efficacy and safety in this setting.

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Publication Details

Journal
Annals of Gastroenterology
Published
2025-01-01
DOI
https://doi.org/10.20524/aog.2025.0992
Primary Topic
Diet and metabolism studies
Type
article
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article

The effects of empagliflozin on diuresis and natriuresis in patients with type 2 diabetes mellitus and liver cirrhosis

Christos Siafarikas
Annals of Gastroenterology
Diet and metabolism studies
article

The effects of empagliflozin on diuresis and natriuresis in patients with type 2 diabetes mellitus and liver cirrhosis

Christos Siafarikas
article en

Abstract

Up to 6 months' empagliflozin administration in patients with cirrhosis and T2DM seems safe and increases urine output and FE<sub>Na</sub>, but its impact on renal function requires further investigation. Larger randomized controlled trials are needed to confirm its long-term efficacy and safety in this setting.

Annals of GastroenterologyVol. 38(5)
National and Kapodistrian University of Athens (GR), Laiko General Hospital of Athens (GR)
Good health and well-being
Openalex Percentile: Top 72%
Diet and metabolism studies
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