Identification of Small Molecule Inhibitors Targeting PD-L1 Protein Using Computational Tools and an Experimental Assay
The findings present optimised small-molecule inhibitors targeting the PD-1/PD-L1 pathway, which could serve as effective immune checkpoint inhibitors. This work provides valuable insight into therapeutic solutions in addressing unmet medical needs in the oncology field.
Authors
- Shymaa Damfo (ORCID: https://orcid.org/0000-0002-2070-7770)
- Almohanad A. Alkayyal (ORCID: https://orcid.org/0000-0001-7042-5985)
- Ahmad Bakur Mahmoud (ORCID: https://orcid.org/0000-0002-1515-2352)
Institutions
- Taibah University (SA)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-08-28
- DOI
- https://doi.org/10.21873/anticanres.17733
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00