Comparative Antitumor Efficacy and Toxicity Profile of SCC5, An Ag(I) <i>N</i>-Heterocyclic Carbene Complex, Relative to Platinum-based Chemotherapeutics
SCC5 maintains broad-spectrum antiproliferative activity with markedly improved <i>in vivo</i> tolerability compared to platinum drugs. These findings support continued preclinical development of SCC5 as a novel silver-based chemotherapeutic.
Authors
- Joseph A. Bauer (ORCID: https://orcid.org/0000-0003-4972-6008)
- Annette M. Sysel
- Michael Dunphy
Institutions
- Walsh University (US)
- Nitric Oxide Services (United States) (US)
- Bauer Research Foundation (US)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-08-28
- DOI
- https://doi.org/10.21873/anticanres.17727
- Primary Topic
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Akron