SOD2-mediated TMZ-resistant Glioblastoma Cells Exhibit Cross-resistance to Irradiation

SOD2 contributes to both TMZ and radiation resistance in GBM. Targeting resistance-associated pathways may offer a promising strategy to improve the efficacy of radiochemotherapy in treatment-refractory glioblastoma.

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Publication Details

Journal
Anticancer Research
Published
2025-08-28
DOI
https://doi.org/10.21873/anticanres.17722
Citations
3
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
Field-Weighted Citation Impact
2.81
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article

SOD2-mediated TMZ-resistant Glioblastoma Cells Exhibit Cross-resistance to Irradiation

P.-Y. Chung, Chia-Hung Chien, King‐Jen Chang, Jiin‐Haur Chuang et al.
3 citations
Anticancer Research
Cancer, Hypoxia, and Metabolism
2.81
article

SOD2-mediated TMZ-resistant Glioblastoma Cells Exhibit Cross-resistance to Irradiation

P.-Y. Chung, Chia-Hung Chien, King‐Jen Chang, Jiin‐Haur Chuang, Mingsheng Liu, Jan‐Show Chu, Wei‐Ting Hsueh
article en
3 citations

Abstract

SOD2 contributes to both TMZ and radiation resistance in GBM. Targeting resistance-associated pathways may offer a promising strategy to improve the efficacy of radiochemotherapy in treatment-refractory glioblastoma.

Anticancer ResearchVol. 45(9)
National Cheng Kung University (TW), I-Shou University (TW)
Openalex Percentile: Top 9%
Cancer, Hypoxia, and Metabolism
2.81
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