Prediction System for <i>KRAS</i> Mutation Detection in Circulating Tumor DNA in Unresectable Pancreatic Cancer
Our prediction system effectively stratified patients by the likelihood of <i>KRAS</i> mutation detection, offering a practical tool for selecting candidates for liquid biopsy. These findings underscore the importance of personalized approaches in unresectable PC management and suggest that patients without these key clinical factors may not benefit from ctDNA testing. Future studies should validate this model in larger cohorts.
Authors
- Hiroshi Shimizu (ORCID: https://orcid.org/0000-0002-4869-502X)
- Kento Osawa
- Mitsuru Sugimoto (ORCID: https://orcid.org/0000-0002-4223-613X)
- Hiromasa Ohira (ORCID: https://orcid.org/0000-0003-4331-0634)
- Kentaro Sato (ORCID: https://orcid.org/0000-0001-6706-2175)
- Rei Suzuki (ORCID: https://orcid.org/0000-0002-4049-0484)
- Hiroyuki Asama (ORCID: https://orcid.org/0000-0002-0102-0404)
- Rei Ohira
Institutions
- Fukushima Medical University (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-08-28
- DOI
- https://doi.org/10.21873/anticanres.17751
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00