Bidirectional shifts in Pm20d1 expression impact thermogenesis and metabolism
Thus, PM20D1 plays a bidirectional role in regulating thermogenesis and body mass, and, at least in part, variants in the promoter region can partially explain the differences in PM20D1 expression and its impact on the metabolic phenotype.
Authors
- Lı́cio A. Velloso (ORCID: https://orcid.org/0000-0002-4806-7218)
- Fernando Valdivieso‐Rivera (ORCID: https://orcid.org/0000-0001-5044-197X)
- Carlos H. Sponton (ORCID: https://orcid.org/0000-0003-4284-8176)
- Milena Monfort‐Pires (ORCID: https://orcid.org/0000-0002-1652-8083)
- Guilherme Nogueira (ORCID: https://orcid.org/0000-0001-8659-6236)
- Roger F. Castilho (ORCID: https://orcid.org/0000-0003-2338-8717)
- Bruna Bombassaro (ORCID: https://orcid.org/0000-0002-8670-8119)
- Ariane Maria Zanesco (ORCID: https://orcid.org/0000-0003-4842-1421)
- Ana L. Gallo-Ferraz (ORCID: https://orcid.org/0000-0003-4117-0957)
- Marcela Reymond Simoes
- Marcos Vinicius da Cruz
- Nayra Fernanda-Oliveira
Institutions
- Universidade de São Paulo (BR)
- Universidade Estadual de Campinas (UNICAMP) (BR)
- Turku PET Centre (FI)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1186/s10020-025-01345-9
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo