Retrospective review of patient factors impacting free-breathing respiratory motion magnitude for MR-guided radiotherapy

Patient factors may influence motion management strategy selection for abdominal stereotactic ablative radiotherapy (SABR). This retrospective evaluation investigated the impact of body mass index (BMI), sex, and cirrhosis in 16 patients imaged with cine-magnetic resonance imaging (MRI) on a 1.5 T magnetic resonance linear accelerator (MR Linac). Male patients, those with cirrhosis, and higher BMI tended to exhibit greater motion magnitude, although this was not statistically significant, suggesting that these patients should be prioritised for motion management strategies. Further investigation in larger cohorts is warranted to confirm these trends and guide personalised motion management in abdominal radiotherapy.

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Publication Details

Journal
Technical Innovations & Patient Support in Radiation Oncology
Published
2025-08-28
DOI
https://doi.org/10.1016/j.tipsro.2025.100339
Primary Topic
Advanced Radiotherapy Techniques
Type
article
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article

Retrospective review of patient factors impacting free-breathing respiratory motion magnitude for MR-guided radiotherapy

Holly Egan, C. Eccles, Ananya Choudhury, Mairéad Daly et al.
Technical Innovations & Patient Support in Radiation Oncology
Advanced Radiotherapy Techniques
article

Retrospective review of patient factors impacting free-breathing respiratory motion magnitude for MR-guided radiotherapy

Holly Egan, C. Eccles, Ananya Choudhury, Mairéad Daly, Ganesh Radhakrishna
article en

Abstract

Patient factors may influence motion management strategy selection for abdominal stereotactic ablative radiotherapy (SABR). This retrospective evaluation investigated the impact of body mass index (BMI), sex, and cirrhosis in 16 patients imaged with cine-magnetic resonance imaging (MRI) on a 1.5 T magnetic resonance linear accelerator (MR Linac). Male patients, those with cirrhosis, and higher BMI tended to exhibit greater motion magnitude, although this was not statistically significant, suggesting that these patients should be prioritised for motion management strategies. Further investigation in larger cohorts is warranted to confirm these trends and guide personalised motion management in abdominal radiotherapy.

Technical Innovations & Patient Support in Radiation OncologyVol. 35
University of Manchester (GB), The Christie NHS Foundation Trust (GB)
Zero hunger
Openalex Percentile: Top 71%
Advanced Radiotherapy Techniques
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