Higher Acceptability of the Monthly Dapivirine Ring Versus Daily Oral Pre-Exposure Prophylaxis Among Adolescent Girls and Young Women in Sub-Saharan Africa in the REACH Trial

The dapivirine ring was highly acceptable to substantially more individuals than oral PrEP, although a significant minority rated oral PrEP highly, even after using the ring. As has been found in the contraceptive field, offering AGYW a choice of PrEP products is likely to increase the use of any HIV prevention method in this vulnerable population.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2025-08-28
DOI
https://doi.org/10.1097/qai.0000000000003756
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.00
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article

Higher Acceptability of the Monthly Dapivirine Ring Versus Daily Oral Pre-Exposure Prophylaxis Among Adolescent Girls and Young Women in Sub-Saharan Africa in the REACH Trial

Barbara Friedland, Erica N. Browne, Pippa Macdonald, Sharon L. Hillier et al.
JAIDS Journal of Acquired Immune Deficiency Syndromes
HIV/AIDS Research and Interventions
article

Higher Acceptability of the Monthly Dapivirine Ring Versus Daily Oral Pre-Exposure Prophylaxis Among Adolescent Girls and Young Women in Sub-Saharan Africa in the REACH Trial

Barbara Friedland, Erica N. Browne, Pippa Macdonald, Sharon L. Hillier, Sherri Johnson, Nomsa Mhlanga, Tara McClure, Gonasagrie Nair, Kenneth Ngure, Sarah T. Roberts, Ariane van der Straten, Siyanda Tenza, Rita Nakalega, Connie Celum, Danny Szydlo, Cynthia Nombeko Mpongo
article en

Abstract

The dapivirine ring was highly acceptable to substantially more individuals than oral PrEP, although a significant minority rated oral PrEP highly, even after using the ring. As has been found in the contraceptive field, offering AGYW a choice of PrEP products is likely to increase the use of any HIV prevention method in this vulnerable population.

JAIDS Journal of Acquired Immune Deficiency SyndromesVol. 100(5)
Family Health International 360 (US), Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA), Infectious Disease Research Institute (US), Desmond Tutu HIV Foundation (ZA), University of Zimbabwe (ZW), University of Cape Town (ZA), University of Washington (US), Stellenbosch University (ZA), Jomo Kenyatta University of Agriculture and Technology (KE), San Francisco AIDS Foundation (US), Fred Hutch Cancer Center (US), Magee-Womens Hospital (US), MUJHU Research Collaboration (UG), Kensington Health (CA), Anova Health Institute (ZA), Population Council (US), Atmospheric and Space Technology Research Associates (United States) (US), St. Mary's Medical Center (US), Perinatal HIV Research Unit (ZA)
Openalex Percentile: Top 73%
HIV/AIDS Research and Interventions
DOIOpen Access PDFOpenAlex
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