Cross-Layer Design and Design Automation for In-Memory Computing Based on Nonvolatile Memory Technologies

Data transfer between processors and memory remains a critical bottleneck in improving application performance on traditional computing hardware, particularly for data-intensive workloads such as machine learning, bioinformatics, and security applications. In-memory computing (IMC), a paradigm where a substantial portion of data processing occurs directly within memory, has emerged as a promising solution to mitigate this bottleneck. The advancement of emerging non-volatile memory (NVM) technologies has further accelerated the development of IMC hardware fabrics. However, harnessing the full potential of IMC requires a cross-layer design approach that spans memory technologies, circuits, architectures, and systems. Essential cross-layer tools—including modeling and simulation, data partitioning and mapping, and operation scheduling—play a pivotal role in designing efficient IMC-based hardware. This article reviews key advancements in simulation and design tools for IMC fabrics, with a focus on NVM-based crossbar arrays and content-addressable memories, while highlighting the necessity of cross-layer collaboration. Additionally, we discuss current challenges and emerging opportunities in the field.