Study on the efficacy of combination therapy with rifaximin and <i>Saccharomyces boulardii</i> CNCM I-745 in patients with small intestinal bacterial overgrowth associated with long-term use of proton pump inhibitors
This prospective comparative study demonstrates that combination therapy with rifaximin and <i>Saccharomyces boulardii</i> CNCM I-745 appears more effective than rifaximin monotherapy for SIBO eradication, symptom regression, and QoL improvement in patients with PPI-associated SIBO.
Authors
- R. I. Shaburov (ORCID: https://orcid.org/0000-0001-9741-0150)
- A. K. Fomenko (ORCID: https://orcid.org/0000-0002-1794-7263)
- И. В. Маев (ORCID: https://orcid.org/0000-0001-6114-564X)
- Д. Н. Андреев (ORCID: https://orcid.org/0000-0002-4007-7112)
- Filipp S. Sokolov (ORCID: https://orcid.org/0000-0003-2813-6498)
- Sergei V. Cheremushkin (ORCID: https://orcid.org/0000-0002-0982-2006)
- Н. В. Черемушкина (ORCID: https://orcid.org/0000-0002-6387-1001)
- Mikhail K. Devkota (ORCID: https://orcid.org/0000-0002-3736-4196)
- A. V. Zaborovsky (ORCID: https://orcid.org/0000-0002-7923-9916)
- Д. Т. Дичева (ORCID: https://orcid.org/0000-0001-9224-7382)
- Sergei V. Tsaregorodtsev (ORCID: https://orcid.org/0000-0002-0254-0516)
- Artem V. Vychkin
Institutions
- Central Clinical Hospital No 2 named Semashko (RU)
Publication Details
- Journal
- Terapevticheskii arkhiv
- Published
- 2025-08-28
- DOI
- https://doi.org/10.26442/00403660.2025.08.203301
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00