The Impact of Worsening Nutritional Status in Neoadjuvant Chemotherapy on Postoperative Outcomes in Esophageal Cancer

Although NAC reduces tumor burden and eliminates micrometastases, it potentially worsens nutritional status. Chemotherapy-induced hematologic toxicities are a risk factor for this decline. Therefore, comprehensive nutritional assessment and timely intervention during NAC are essential to optimize patient outcomes.

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Publication Details

Journal
In Vivo
Published
2025-08-28
DOI
https://doi.org/10.21873/invivo.14084
Citations
1
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
Field-Weighted Citation Impact
2.01
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article

The Impact of Worsening Nutritional Status in Neoadjuvant Chemotherapy on Postoperative Outcomes in Esophageal Cancer

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article

The Impact of Worsening Nutritional Status in Neoadjuvant Chemotherapy on Postoperative Outcomes in Esophageal Cancer

Zenichiro Saze, Hiroki Yago, Tomohiro Kikuchi, Akira Matsuishi, Hajime Matsuida, Hiroyuki Hanayama, Azuma Nirei, Makoto Hasegawa, Koji Kono, Hiroya Suzuki, Dai Mitsui, Yuya Maruyama
article en
1 citations

Abstract

Although NAC reduces tumor burden and eliminates micrometastases, it potentially worsens nutritional status. Chemotherapy-induced hematologic toxicities are a risk factor for this decline. Therefore, comprehensive nutritional assessment and timely intervention during NAC are essential to optimize patient outcomes.

In VivoVol. 39(5)
Fukushima Medical University (JP)
Zero hunger
Openalex Percentile: Top 12%
Esophageal Cancer Research and Treatment
2.01
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