The Role of Salvage Chemotherapy on Survival Outcomes Following Immune Checkpoint Inhibitor Therapy in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
SCT after ICI failure significantly improves survival in R/M HNSCC, particularly when using PTX+Cmab. Patients who received SCT had substantially better outcomes than those who did not. ECOG PS and sarcopenia status should be considered in treatment selection.
Authors
- M Umemoto
- TAKAYUKI KIMURA
- MUTSUKAZU KITANO
- Takahiro Wakasaki (ORCID: https://orcid.org/0000-0001-7736-9162)
- Ryuji Yasumatsu (ORCID: https://orcid.org/0000-0001-6199-0341)
- Hisatomo Tamaki
- Mitsuo Satõ (ORCID: https://orcid.org/0000-0003-4498-7428)
- Michi Kawamoto (ORCID: https://orcid.org/0000-0002-5760-4935)
- Daisuke Abe (ORCID: https://orcid.org/0000-0002-6160-7223)
- Satoru Koike
- Sayumi Konya
Institutions
- Kindai University Hospital (JP)
- Kindai University (JP)
Publication Details
- Journal
- In Vivo
- Published
- 2025-08-28
- DOI
- https://doi.org/10.21873/invivo.14100
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science