γ-Aminobutyric Acid–mediated Parafacial Zone: Integrating Consciousness and Respiratory Control in Sevoflurane Anesthesia

The GABAergic parafacial zone is a shared critical node regulating both respiration and consciousness during sevoflurane anesthesia. Its activation suppresses both, helping explain anesthesia-related respiratory depression.

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Publication Details

Journal
Anesthesiology
Published
2025-08-28
DOI
https://doi.org/10.1097/aln.0000000000005735
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
0.00
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article

γ-Aminobutyric Acid–mediated Parafacial Zone: Integrating Consciousness and Respiratory Control in Sevoflurane Anesthesia

Shouyang Yu, Zhenbo Deng, Linlin Luo, Zhiguang Qin et al.
Anesthesiology
Anesthesia and Sedative Agents
article

γ-Aminobutyric Acid–mediated Parafacial Zone: Integrating Consciousness and Respiratory Control in Sevoflurane Anesthesia

Shouyang Yu, Zhenbo Deng, Linlin Luo, Zhiguang Qin, Mei Chen, Tianyuan Luo, Jiang Zhu, Ying Wang, Haiying Wang, Jia Li, Tian Yu, Xuejiao Dou, Junli Jiang, Yuanli Pi
article en

Abstract

The GABAergic parafacial zone is a shared critical node regulating both respiration and consciousness during sevoflurane anesthesia. Its activation suppresses both, helping explain anesthesia-related respiratory depression.

AnesthesiologyVol. 144(1)
Zunyi Medical University (CN), Affiliated Hospital of Zunyi Medical College (CN)
Openalex Percentile: Top 65%
Anesthesia and Sedative Agents
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