Juvenile Nasopharyngeal Angiofibroma With Skull Base Involvement: A Radiological and Clinical Insight Into a Classic Adolescent Presentation

Juvenile nasopharyngeal angiofibroma (JNA) represents a rare, histologically benign yet locally aggressive vascular tumor that predominantly arises in adolescent males. Given its propensity for invasive growth and involvement of critical anatomical structures, precise radiological evaluation is vital prior to any intervention. We present the case of a 13-year-old male who experienced progressive bilateral nasal blockage and recurrent epistaxis predominantly on the left side. Magnetic resonance imaging (MRI) identified a vividly enhancing lesion centered at the left sphenopalatine foramen, with extensions into adjacent sinuses, the pterygopalatine fossa, infratemporal fossa, and early skull base erosion. This case highlights the critical diagnostic and staging role of MRI in JNA, illustrating how characteristic imaging findings inform diagnosis, classification, and surgical planning.

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Publication Details

Journal
Cureus
Published
2025-08-28
DOI
https://doi.org/10.7759/cureus.91191
Primary Topic
Head and Neck Surgical Oncology
Type
article
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article

Juvenile Nasopharyngeal Angiofibroma With Skull Base Involvement: A Radiological and Clinical Insight Into a Classic Adolescent Presentation

Meriem Fikri, Oumaima Boukhlouf, Firdaous Touarsa, M. Jiddane et al.
Cureus
Head and Neck Surgical Oncology
article

Juvenile Nasopharyngeal Angiofibroma With Skull Base Involvement: A Radiological and Clinical Insight Into a Classic Adolescent Presentation

Meriem Fikri, Oumaima Boukhlouf, Firdaous Touarsa, M. Jiddane, Zineb Labbi
article en

Abstract

Juvenile nasopharyngeal angiofibroma (JNA) represents a rare, histologically benign yet locally aggressive vascular tumor that predominantly arises in adolescent males. Given its propensity for invasive growth and involvement of critical anatomical structures, precise radiological evaluation is vital prior to any intervention. We present the case of a 13-year-old male who experienced progressive bilateral nasal blockage and recurrent epistaxis predominantly on the left side. Magnetic resonance imaging (MRI) identified a vividly enhancing lesion centered at the left sphenopalatine foramen, with extensions into adjacent sinuses, the pterygopalatine fossa, infratemporal fossa, and early skull base erosion. This case highlights the critical diagnostic and staging role of MRI in JNA, illustrating how characteristic imaging findings inform diagnosis, classification, and surgical planning.

CureusVol. 17(8)
Mohammed V University (MA), Orthopedic Specialty Hospital (US), Hôpital Ibn Sina-Rabat (MA), Ibn Sina Hospital (KW)
Openalex Percentile: Top 64%
Head and Neck Surgical Oncology
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Juvenile Nasopharyngeal Angiofibroma With Skull Base Involvement: A Radiological and Clinical Insight Into a Classic Adolescent Presentation — Meriem Fikri, Oumaima Boukhlouf, et al. · Cureus (2025) | TGRS Research Map | TGRS