Predictors of extrapyramidal side effects among patients taking antipsychotic medication at Mekelle psychiatry units, Northern Ethiopia, 2023: unmatched case-control study

Our study revealed, being female, single, stigma, combination first-generation antipsychotic drug, having mental illness history, Khat chewing practice/ behavior and Alcohol intake in the last 3 months were significant factors of Extrapyramidal Side Effects. Psychiatric professionals should be assessing the predictors of Extrapyramidal Side Effects especially, combination of first-generation antipsychotic drugs, substance use with antipsychotic drugs and management comorbid diagnosis routinely is strongly recommended.