Sex-Related Differences in Non–Pulmonary Vein Triggers During Initial Atrial Fibrillation Ablation
In this cohort study of 2038 patients, women exhibited a higher prevalence of non-PV triggers, especially from the right atrium, than men. Women with non-PV triggers were more likely to have multiple triggers and worse postablation outcomes. These findings highlight the importance of performing systematic provocation protocol with increased vigilance among women, particularly for those with additional risk factors.
Authors
- Erica S. Zado (ORCID: https://orcid.org/0000-0001-7331-448X)
- Matthew Craig Hyman (ORCID: https://orcid.org/0000-0002-4050-6925)
- David S. Frankel (ORCID: https://orcid.org/0000-0001-9276-4857)
- Robert D. Schaller (ORCID: https://orcid.org/0000-0001-8608-7247)
- David J. Callans (ORCID: https://orcid.org/0000-0001-6823-6149)
- David Lin (ORCID: https://orcid.org/0000-0002-0820-5049)
- Oriol Rodríguez-Queraltó (ORCID: https://orcid.org/0000-0003-2746-3243)
- Balaram Krishna J. Hanumanthu (ORCID: https://orcid.org/0000-0003-2637-9736)
- Francis E. Marchlinski (ORCID: https://orcid.org/0000-0001-7962-9423)
- Frédéric Anselme (ORCID: https://orcid.org/0000-0002-2130-9790)
- Gregory E. Supple (ORCID: https://orcid.org/0000-0002-2248-5139)
- Andres A. Enriquez (ORCID: https://orcid.org/0000-0002-8146-360X)
- Alireza Oraii (ORCID: https://orcid.org/0000-0002-2422-2930)
- Poojita Shivamurthy (ORCID: https://orcid.org/0000-0002-8260-3221)
- Adrian Petzl (ORCID: https://orcid.org/0000-0002-8935-3560)
- Saman Nazarian (ORCID: https://orcid.org/0000-0002-8369-0259)
- Corentin Chaumont (ORCID: https://orcid.org/0000-0001-7188-2686)
- Cory M. Tschabrunn (ORCID: https://orcid.org/0000-0003-2887-1150)
- Timothy M. Markman (ORCID: https://orcid.org/0000-0002-3155-2006)
- Michael P. Riley (ORCID: https://orcid.org/0009-0001-9020-9507)
- Ramanan Kumareswaran
- Fermin Carlos Garcia (ORCID: https://orcid.org/0000-0003-0559-9131)
Institutions
- Inserm (FR)
- Hospital of the University of Pennsylvania (US)
- Université de Rouen Normandie (FR)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.29527
- Citations
- 2
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Abbott Laboratories
- University of Pennsylvania
- Boston Scientific Corporation
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- Biosense Webster