A rare case report: Bilateral tonsillar primary mantle cell lymphoma with a subcutaneous swelling

Abstract Mantle cell lymphoma (MCL), a subtype of non-Hodgkin’s lymphoma (NHL), accounts for almost 5%–7% of all the NHL diagnosed cases, with 70% of cases seen in men aged between 60 and 70 years. Nearly 25% of the cases show extranodal disease as the primary presentation. Extranodal involvement of Waldeyer’s ring, salivary glands, lacrimal gland, orbit, skin, thyroid, breast, pleura, and spleen is very rare. Cutaneous or subcutaneous lesions or lesions in the oral cavity as presenting features are exceedingly rare, and thorough clinical examination should be done for any other synchronous swellings. Immediate satisfactory evaluation is utmost to provide the patient with the best possible outcome. This case report helps us further broaden our understanding of the spectrum of clinical presentation of MCL. We report a case of primary MCL that presented with bilateral tonsillar enlargement with a subcutaneous left upper back swelling.

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Publication Details

Journal
Annals of Medical Science and Research
Published
2025-05-01
DOI
https://doi.org/10.4103/amsr.amsr_16_25
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
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article

A rare case report: Bilateral tonsillar primary mantle cell lymphoma with a subcutaneous swelling

B. Deepthi, Ankita Pranab Mandal, Nandyala Rukmangadha, Aruna Prayaga
Annals of Medical Science and Research
Lymphoma Diagnosis and Treatment
article

A rare case report: Bilateral tonsillar primary mantle cell lymphoma with a subcutaneous swelling

B. Deepthi, Ankita Pranab Mandal, Nandyala Rukmangadha, Aruna Prayaga
article en

Abstract

Abstract Mantle cell lymphoma (MCL), a subtype of non-Hodgkin’s lymphoma (NHL), accounts for almost 5%–7% of all the NHL diagnosed cases, with 70% of cases seen in men aged between 60 and 70 years. Nearly 25% of the cases show extranodal disease as the primary presentation. Extranodal involvement of Waldeyer’s ring, salivary glands, lacrimal gland, orbit, skin, thyroid, breast, pleura, and spleen is very rare. Cutaneous or subcutaneous lesions or lesions in the oral cavity as presenting features are exceedingly rare, and thorough clinical examination should be done for any other synchronous swellings. Immediate satisfactory evaluation is utmost to provide the patient with the best possible outcome. This case report helps us further broaden our understanding of the spectrum of clinical presentation of MCL. We report a case of primary MCL that presented with bilateral tonsillar enlargement with a subcutaneous left upper back swelling.

Annals of Medical Science and ResearchVol. 4(2)
Sri Venkateswara Institute of Medical Sciences (IN)
Openalex Percentile: Top 68%
Lymphoma Diagnosis and Treatment
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A rare case report: Bilateral tonsillar primary mantle cell lymphoma with a subcutaneous swelling — B. Deepthi, Ankita Pranab Mandal, et al. · Annals of Medical Science and Research (2025) | TGRS Research Map | TGRS