Surgical Outcomes of Lenvatinib Treatment Followed by Liver Resection for Advanced Hepatocellular Carcinoma Larger than 10 cm

Preoperative lenvatinib treatment followed by hepatectomy for large HCC (> 10 cm) may reduce recurrence, particularly distant metastases, and potentially improve long-term survival. This approach may be a promising strategy for large HCCs, which traditionally have a poor prognosis with upfront surgery alone.

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Publication Details

Journal
Cancers
Published
2025-08-28
DOI
https://doi.org/10.3390/cancers17172818
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

Surgical Outcomes of Lenvatinib Treatment Followed by Liver Resection for Advanced Hepatocellular Carcinoma Larger than 10 cm

Katsuro Enomoto, Yuki Adachi, T Takizawa, Koji Imai et al.
Cancers
Hepatocellular Carcinoma Treatment and Prognosis
article

Surgical Outcomes of Lenvatinib Treatment Followed by Liver Resection for Advanced Hepatocellular Carcinoma Larger than 10 cm

Katsuro Enomoto, Yuki Adachi, T Takizawa, Koji Imai, Hideki Yokoo, Hiroyuki Takahashi, Shoichiro Mizukami, Hiroki Takahata, Kai Makino
article en

Abstract

Preoperative lenvatinib treatment followed by hepatectomy for large HCC (> 10 cm) may reduce recurrence, particularly distant metastases, and potentially improve long-term survival. This approach may be a promising strategy for large HCCs, which traditionally have a poor prognosis with upfront surgery alone.

CancersVol. 17(17)
Asahikawa Medical University (JP)
Openalex Percentile: Top 69%
Hepatocellular Carcinoma Treatment and Prognosis
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