Steatohepatitis alters lymphocytes cytotoxicity and localization, accelerating colorectal liver metastases
This research underscores the crucial influence of diet-induced immune changes on CRLM establishment and progression. It illustrates that the co-localization of immune cells within liver metastases significantly affects their functionality, highlighting potential therapeutic strategies to balance immune exhaustion and activation.
Authors
- Eyal Yehezkel (ORCID: https://orcid.org/0000-0001-9425-4228)
- Nathalie Abudi
- Rinat Abramovitch (ORCID: https://orcid.org/0000-0003-1126-7467)
- Adi S. Yehezkel
Institutions
- Hadassah Medical Center (IL)
Publication Details
- Journal
- Neoplasia
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1016/j.neo.2025.101222
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Israel Science Foundation