The Influence of Maternal <i>Staphylococcus aureus</i> Anti-Hla Neutralizing Antibody on Infant Skin and Soft Tissue Development in the First Year of Life
S. aureus colonization occurs early in life, with over 40% of infants colonized by 1-month. These results are the first to demonstrate an association between higher transplacental anti-Hla NAb and protection against infant SSTI in the first year of life. Overall, these findings support Hla as a promising vaccine target.
Authors
- Mary G. Boyle
- Scott L. Crick
- Carol Kao
- Alaina Schneider
- Kristine M. Wylie (ORCID: https://orcid.org/0000-0002-2504-0661)
- Stephanie A. Fritz (ORCID: https://orcid.org/0000-0002-8602-5879)
- Juliane Bubeck Wardenburg (ORCID: https://orcid.org/0000-0002-2755-3348)
- Rachel Uhlir
Institutions
- Washington University in St. Louis (US)
- HealthInsight (US)
- University of Brighton (GB)
Publication Details
- Journal
- Journal of the Pediatric Infectious Diseases Society
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1093/jpids/piaf077
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00