Knockdown of TIM1 enhances platinum chemosensitivity and inhibits progression through the MAPK signaling pathway in gastric cancer
Overall, TIM1 functions as an oncogene in GC. Knockdown of TIM1 enhances platinum chemosensitivity and inhibits malignant behavior in GC through the MAPK signaling pathway. These findings reveal a molecular mechanism contributing to chemotherapy resistance and suggest a therapeutic strategy for enhancing chemotherapy.
Authors
- Congkai Zhang
Institutions
- Yangtze University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- American Journal of Translational Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.62347/vaff5386
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province