DABCO-catalysed highly diastereoselective synthesis of 1,3-indandione containing fully saturated spirocyclopentanes involving 2-(2′-ketoalkyl)-1,3-indandiones and nitrostyrenes
Highly functionalized 1,3-indandione containing spirocyclopentanes has been synthesized by reacting nitrostyrenes with 2-(2'-ketoalkyl)-1,3-indandiones using a catalytic amount of DABCO. The resultant products possess three consecutive chiral centres in addition to a spirocyclic centre and are obtained in a highly diastereoselective manner using a catalytic amount of the organic base, DABCO.
Authors
- Barla Thirupathi (ORCID: https://orcid.org/0000-0002-2324-0870)
- Kamrul Islam (ORCID: https://orcid.org/0000-0001-8979-9899)
- Gitanjali Mishra (ORCID: https://orcid.org/0000-0002-0621-921X)
- Arundhuti Chakraborty
- Missa Saril Bobonga
Institutions
- Indian Institute of Science Education and Research Berhampur (IN)
Publication Details
- Journal
- RSC Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ra04224k
- Citations
- 1
- Primary Topic
- Asymmetric Synthesis and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- Indian Institute of Science Education and Research Mohali
- Science and Engineering Research Board