Three-year experience with GLP-2 analog in intestinal rehabilitation for pediatric-onset short bowel syndrome

GLP-2 analog therapy, which is based on intestinal rehabilitation, contributed to a sustained reduction in PN and enhanced clinical outcomes over three years, particularly in adult SBS patients. Continuous GLP-2 analog therapy might improve quality of life in paediatric-onset SBS.

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Publication Details

Journal
Pediatric Surgery International
Published
2025-08-28
DOI
https://doi.org/10.1007/s00383-025-06154-z
Primary Topic
Clinical Nutrition and Gastroenterology
Type
article
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article

Three-year experience with GLP-2 analog in intestinal rehabilitation for pediatric-onset short bowel syndrome

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Three-year experience with GLP-2 analog in intestinal rehabilitation for pediatric-onset short bowel syndrome

Kōichi Deguchi, Hiroomi Okuyama, Naoko Uga, Takehisa Ueno, Yuko Tazuke, Takaharu Oue, Kengo Nakahata, Takeshi Kimura
article en

Abstract

GLP-2 analog therapy, which is based on intestinal rehabilitation, contributed to a sustained reduction in PN and enhanced clinical outcomes over three years, particularly in adult SBS patients. Continuous GLP-2 analog therapy might improve quality of life in paediatric-onset SBS.

Pediatric Surgery InternationalVol. 41(1)
Osaka Gakuin University (JP), Hyogo Medical University (JP), Hyogo University (JP), The University of Osaka (JP)
Zero hunger
Openalex Percentile: Top 73%
Clinical Nutrition and Gastroenterology
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