The Charité protocol for surveillance, treatment and after-care management in women with Lynch syndrome

A holistic, multidisciplinary approach is essential for the management of LS patients in gynecological oncology. The structured consultation model developed at Charité facilitates personalized surveillance, risk-adapted prevention, and evidence-based therapy strategies. Future studies and clinical trials should further investigate screening protocols, therapeutic interventions, and the role of LS patients in targeted treatment approaches. This guideline serves as a preliminary framework and will be continuously adapted as new research emerges.

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Publication Details

Journal
Archives of Gynecology and Obstetrics
Published
2025-08-28
DOI
https://doi.org/10.1007/s00404-025-08112-5
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
0.00

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article

The Charité protocol for surveillance, treatment and after-care management in women with Lynch syndrome

Radoslav Chekerov, S Daum, Jalid Sehouli, Lukas Chinczewski et al.
Archives of Gynecology and Obstetrics
Genetic factors in colorectal cancer
article

The Charité protocol for surveillance, treatment and after-care management in women with Lynch syndrome

Radoslav Chekerov, S Daum, Jalid Sehouli, Lukas Chinczewski, Claus‐Eric Ott
article en

Abstract

A holistic, multidisciplinary approach is essential for the management of LS patients in gynecological oncology. The structured consultation model developed at Charité facilitates personalized surveillance, risk-adapted prevention, and evidence-based therapy strategies. Future studies and clinical trials should further investigate screening protocols, therapeutic interventions, and the role of LS patients in targeted treatment approaches. This guideline serves as a preliminary framework and will be continuously adapted as new research emerges.

Archives of Gynecology and ObstetricsVol. 312(5)
Charité - Universitätsmedizin Berlin (DE)
Charité – Universitätsmedizin Berlin
Openalex Percentile: Top 68%
Genetic factors in colorectal cancer
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