The Charité protocol for surveillance, treatment and after-care management in women with Lynch syndrome
A holistic, multidisciplinary approach is essential for the management of LS patients in gynecological oncology. The structured consultation model developed at Charité facilitates personalized surveillance, risk-adapted prevention, and evidence-based therapy strategies. Future studies and clinical trials should further investigate screening protocols, therapeutic interventions, and the role of LS patients in targeted treatment approaches. This guideline serves as a preliminary framework and will be continuously adapted as new research emerges.
Authors
- Radoslav Chekerov (ORCID: https://orcid.org/0000-0001-9535-3033)
- S Daum (ORCID: https://orcid.org/0000-0003-0060-6013)
- Jalid Sehouli
- Lukas Chinczewski (ORCID: https://orcid.org/0000-0002-6148-5887)
- Claus‐Eric Ott (ORCID: https://orcid.org/0000-0003-3627-3791)
Institutions
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1007/s00404-025-08112-5
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Charité – Universitätsmedizin Berlin